Mineralocorticoid Receptor Antagonists Cause Natriuresis in the Absence of Aldosterone’ in press in Hypertension (AHA)

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Yujiro Maeoka 1, Xiao-Tong Su 1, Wen-Hui Wang 2, Xin-Peng Duan 2, Avika Sharma 1, Na Li 3, Olivier Staub 3 4, James A McCormick 1, David H Ellison 1 4 5

Dr. David Ellison presented an invited lecture at Experimental Biology in April 2022, entitled ‘Direct & Indirect Calcineurin Inhibitor Toxicity’

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Combined Kelch-like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice

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Maeoka Y, Ferdaus MZ, Cornelius RJ, Sharma A, Su XT, Miller LN, Robertson JA, Gurley SB, Yang CL, Ellison DH, McCormick JA.

J Am Soc Nephrol. 2022 Mar;33(3):584-600. doi: 10.1681/ASN.2021081099. Epub 2022 Jan 21.PMID: 35064051

Please Welcome Marissa Gutierrez to Dr. Ellison Lab. She is a new Research Assistant, and a new University of Oregon graduate

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Please Welcome Jeremiah Reyes to Dr. Ellison Lab. He is an MD/PhD student from the University of the Philippines Manilla College of Medicine, who is completing his thesis work in the laboratory, studying the mechanisms by which NCC regulates calcium and magnesium transport.

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Insights into Salt Handling and Blood Pressure.

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Ellison DH, Welling P.N Engl J Med. 2021 Nov 18;385(21):1981-1993. doi: 10.1056/NEJMra2030212.PMID: 34788509 Review. No abstract available.

Compensatory post-diuretic renal sodium reabsorption is not a dominant mechanism of diuretic resistance in acute heart failure

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Cox ZL, Rao VS, Ivey-Miranda JB, Moreno-Villagomez J, Mahoney D, Ponikowski P, Biegus J, Turner JM, Maulion C, Bellumkonda L, Asher JL, Parise H, Wilson PF, Ellison DH, Wilcox CS, Testani JM.Eur Heart J. 2021 Sep 16:ehab620. doi: 10.1093/eurheartj/ehab620. Online ahead of print.PMID: 34529781

SGLT2-inhibitors, hemodynamics, and kidney protection.

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Ellison DH.
Am J Physiol Renal Physiol. 2021 Mar 22. doi: 10.1152/ajprenal.00092.2021. Online ahead of print.
PMID: 33749325 No abstract available.

Roles of WNK4 and SPAK in K+ mediated dephosphorylation of the sodium chloride cotransporter.

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Mukherjee A, Yang CL, McCormick JA, Martz K, Sharma A, Ellison DH.
Am J Physiol Renal Physiol. 2021 Mar 15. doi: 10.1152/ajprenal.00459.2020. Online ahead of print.
PMID: 33719576

Distal convoluted tubule Cl- concentration is modulated via K+ channels and transporters.

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Su XT, Klett NJ, Sharma A, Allen CN, Wang WH, Yang CL, Ellison DH.
Am J Physiol Renal Physiol. 2020 Sep 1;319(3):F534-F540. doi: 10.1152/ajprenal.00284.2020. Epub 2020 Jul 27.
PMID: 32715757