2022
Blood pressure effects of sodium transport along the distal nephron.
Castañeda-Bueno M, Ellison DH. Kidney Int. 2022 Dec;102(6):1247-1258. doi: 10.1016/j.kint.2022.09.009. Epub 2022 Oct 10. PMID: 36228680; PMCID: PMC9754644. [Article] Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity.
Neumann C, Rosenbaek LL, Flygaard RK, Habeck M, Karlsen JL, Wang Y, Lindorff-Larsen K, Gad HH, Hartmann R, Lyons JA, Fenton RA, EMBO J. 2022 Dec 1;41(23):e110169. doi: 10.15252/embj.2021110169. Epub 2022 Oct 14. PMID: 36239040; PMCID: PMC9713717. [Article] Multiple molecular mechanisms are involved in the activation of the kidney sodium-chloride cotransporter by hypokalemia.
Murillo-de-Ozores AR, Carbajal-Contreras H, Magaña-Ávila GR, Valdés R, Grajeda-Medina LI, Vázquez N, Zariñán T, López-Saavedra A, Sharma A, Lin DH, Wang WH, Delpire E, Ellison DH, Gamba G, Castañeda-Bueno M. Kidney Int. 2022 Nov;102(5):1030-1041. doi: 10.1016/j.kint.2022.06.027. Epub 2022 Jul 21. PMID: 35870644; PMCID: PMC10411384. [Article] Genetic deletion of the nuclear factor of activated T cells 5 in collecting duct principal cells causes nephrogenic diabetes insipidus.
Petrillo F, Chernyakov D, Esteva-Font C, Poulsen SB, Edemir B, Fenton RA. FASEB J. 2022 Nov;36(11):e22583. doi: 10.1096/fj.202200856R. PMID: 36197017. [Article] Genetic deletion of the nuclear factor of activated T cells 5 in collecting duct principal cells causes nephrogenic diabetes insipidus.
Petrillo F, Chernyakov D, Esteva-Font C, Poulsen SB, Edemir B, Fenton RA. FASEB J. 2022 Nov;36(11):e22583. doi: 10.1096/fj.202200856R. PMID: 36197017. [Article] nhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling
Moseng MA, Su CC, Rios K, Cui M, Lyu M, Glaza P, Klenotic PA, Delpire E, Yu EW. Sci Adv. 2022 Oct 28;8(43):eabq0952. doi: 10.1126/sciadv.abq0952. Epub 2022 Oct 28. PMID: 36306358; PMCID: PMC9616490. [Article] The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter NCC but is not required for a potassium-induced reduction of NCC expression.
Rosenbaek LL, Petrillo F, van Bemmelen MX, Staub O, Murali SK, Fenton RA. Front Physiol. 2022 Sep 7;13:971251. doi: 10.3389/fphys.2022.971251. PMID: 36160843; PMCID: PMC9490057. [Article] Using human urinary extracellular vesicles to study physiological and pathophysiological states and regulation of the sodium chloride cotransporter.
Wu A, Wolley MJ, Fenton RA, Stowasser M. Front Endocrinol (Lausanne). 2022 Aug 29;13:981317. doi: 10.3389/fendo.2022.981317. PMID: 36105401; PMCID: PMC9465297. [Article] n Primary Aldosteronism Acute Potassium Chloride Supplementation Suppresses Abundance and Phosphorylation of the Sodium-Chloride Cotransporter.
Wu A, Wolley MJ, Matthews A, Cowley D, Welling PA, Fenton RA, Stowasser M. Kidney360. 2022 Aug 26;3(11):1909-1923. doi: 10.34067/KID.0003632022. PMID: 36514401; PMCID: PMC9717638. [Article] Potassium homeostasis: sensors, mediators, and targets.
McDonough AA, Fenton RA Pflugers Arch. 2022 Aug;474(8):853-867. doi: 10.1007/s00424-022-02718-3. Epub 2022 Jun 21. PMID: 35727363; PMCID: PMC10163916. [Article] NHE3 in the thick ascending limb is required for sustained but not acute furosemide-induced urinary acidification. Am J Physiol Renal Physiol.
Xue J, Thomas L, Dominguez Rieg JA, Fenton RA, Rieg T. Am J Physiol Renal Physiol. 2022 Aug 1;323(2):F141-F155. doi: 10.1152/ajprenal.00013.2022. Epub 2022 May 30. PMID: 35635321; PMCID: PMC9306792. [Article] Urinary extracellular vesicles: does cargo reflect tissue?
van Heugten MH, Hoorn EJ, Fenton RA. Curr Opin Nephrol Hypertens. 2022 Sep 1;31(5):464-470. doi: 10.1097/MNH.0000000000000822. Epub 2022 Jul 18. PMID: 35894281. [Article] COP9 signalosome deletion promotes renal injury and distal convoluted tubule remodeling.
Cornelius RJ, Nelson JW, Su XT, Yang CL, Ellison DH. Am J Physiol Renal Physiol. 2022 Jul 1;323(1):F4-F19. doi: 10.1152/ajprenal.00436.2021. Epub 2022 May 9. PMID: 35532068; PMCID: PMC9236871. [Article] KCC3a, a Strong Candidate Pathway for K+ Loss in Alkalemia.
Ferdaus MZ, Terker AS, Koumangoye R, Delpire E. Front Cell Dev Biol. 2022 Jul 7;10:931326. doi: 10.3389/fcell.2022.931326. PMID: 35874803; PMCID: PMC9301082. [Article] Mineralocorticoid Receptor Antagonists Cause Natriuresis in the Absence of Aldosterone’ in press in Hypertension (AHA)
Kristensen M, Fenton RA, Poulsen SB. Front Physiol. 2022 Apr 26;13:800055. doi: 10.3389/fphys.2022.800055. PMID: 35557966; PMCID: PMC9086401. [Article] Aldosterone-producing adenoma associated with non-suppressed renin: a case series.
Jansen PM, Stowasser M. J Hum Hypertens 2022;36:376-80. [Article] Acute Intravenous NaCl and Volume Expansion Reduces Sodium-Chloride Cotransporter Abundance and Phosphorylation in Urinary Extracellular Vesicles.
Wu A, Wolley MJ, Wu Q, Cowley D, Palmfeldt J, Welling PA, Fenton RA, Stowasser M. Kidney360. 2022 Mar 1;3(5):910-921. doi: 10.34067/KID.0000362022. PMID: 36128481; PMCID: PMC9438418. [Article] Combined Kelch-like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice
Maeoka Y, Ferdaus MZ, Cornelius RJ, Sharma A, Su XT, Miller LN, Robertson JA, Gurley SB, Yang CL, Ellison DH, McCormick JA. J Am Soc Nephrol. 2022 Mar;33(3):584-600. doi: 10.1681/ASN.2021081099. Epub 2022 Jan 21.PMID: 35064051 [Article] Does the early aldosterone-induced SGK1 play a role in early Kaliuresis?
Al-Qusairi L, Basquin D, Stifanelli M, Welling PA, Staub O. Physiol Rep. 2022 Feb;10(4):e15188. doi: 10.14814/phy2.15188. PMID: 35224872; PMCID: PMC8883148. [Article] Pendrin-null mice develop severe hypokalemia following dietary Na+ and K+ restriction: role of ENaC.
Pham TD, Elengickal AJ, Verlander JW, Al-Qusairi L, Chen C, Abood DC, King SA, Loffing J, Welling PA, Wall SM. Am J Physiol Renal Physiol. 2022 May 1;322(5):F486-F497. doi: 10.1152/ajprenal.00378.2021. Epub 2022 Feb 28. PMID: 35224991; PMCID: PMC8977139. [Article] Low Salt Delivery Triggers Autocrine Release of Prostaglandin E2 From the Aldosterone-Sensitive Distal Nephron in Familial Hyperkalemic Hypertension Mice.
Zapf AM, Grimm PR, Al-Qusairi L, Delpire E, Welling PA. Front Physiol. 2022 Jan 6;12:787323. doi: 10.3389/fphys.2021.787323. PMID: 35069250; PMCID: PMC8770744. [Article]
Castañeda-Bueno M, Ellison DH. Kidney Int. 2022 Dec;102(6):1247-1258. doi: 10.1016/j.kint.2022.09.009. Epub 2022 Oct 10. PMID: 36228680; PMCID: PMC9754644. [Article] Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity.
Neumann C, Rosenbaek LL, Flygaard RK, Habeck M, Karlsen JL, Wang Y, Lindorff-Larsen K, Gad HH, Hartmann R, Lyons JA, Fenton RA, EMBO J. 2022 Dec 1;41(23):e110169. doi: 10.15252/embj.2021110169. Epub 2022 Oct 14. PMID: 36239040; PMCID: PMC9713717. [Article] Multiple molecular mechanisms are involved in the activation of the kidney sodium-chloride cotransporter by hypokalemia.
Murillo-de-Ozores AR, Carbajal-Contreras H, Magaña-Ávila GR, Valdés R, Grajeda-Medina LI, Vázquez N, Zariñán T, López-Saavedra A, Sharma A, Lin DH, Wang WH, Delpire E, Ellison DH, Gamba G, Castañeda-Bueno M. Kidney Int. 2022 Nov;102(5):1030-1041. doi: 10.1016/j.kint.2022.06.027. Epub 2022 Jul 21. PMID: 35870644; PMCID: PMC10411384. [Article] Genetic deletion of the nuclear factor of activated T cells 5 in collecting duct principal cells causes nephrogenic diabetes insipidus.
Petrillo F, Chernyakov D, Esteva-Font C, Poulsen SB, Edemir B, Fenton RA. FASEB J. 2022 Nov;36(11):e22583. doi: 10.1096/fj.202200856R. PMID: 36197017. [Article] Genetic deletion of the nuclear factor of activated T cells 5 in collecting duct principal cells causes nephrogenic diabetes insipidus.
Petrillo F, Chernyakov D, Esteva-Font C, Poulsen SB, Edemir B, Fenton RA. FASEB J. 2022 Nov;36(11):e22583. doi: 10.1096/fj.202200856R. PMID: 36197017. [Article] nhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling
Moseng MA, Su CC, Rios K, Cui M, Lyu M, Glaza P, Klenotic PA, Delpire E, Yu EW. Sci Adv. 2022 Oct 28;8(43):eabq0952. doi: 10.1126/sciadv.abq0952. Epub 2022 Oct 28. PMID: 36306358; PMCID: PMC9616490. [Article] The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter NCC but is not required for a potassium-induced reduction of NCC expression.
Rosenbaek LL, Petrillo F, van Bemmelen MX, Staub O, Murali SK, Fenton RA. Front Physiol. 2022 Sep 7;13:971251. doi: 10.3389/fphys.2022.971251. PMID: 36160843; PMCID: PMC9490057. [Article] Using human urinary extracellular vesicles to study physiological and pathophysiological states and regulation of the sodium chloride cotransporter.
Wu A, Wolley MJ, Fenton RA, Stowasser M. Front Endocrinol (Lausanne). 2022 Aug 29;13:981317. doi: 10.3389/fendo.2022.981317. PMID: 36105401; PMCID: PMC9465297. [Article] n Primary Aldosteronism Acute Potassium Chloride Supplementation Suppresses Abundance and Phosphorylation of the Sodium-Chloride Cotransporter.
Wu A, Wolley MJ, Matthews A, Cowley D, Welling PA, Fenton RA, Stowasser M. Kidney360. 2022 Aug 26;3(11):1909-1923. doi: 10.34067/KID.0003632022. PMID: 36514401; PMCID: PMC9717638. [Article] Potassium homeostasis: sensors, mediators, and targets.
McDonough AA, Fenton RA Pflugers Arch. 2022 Aug;474(8):853-867. doi: 10.1007/s00424-022-02718-3. Epub 2022 Jun 21. PMID: 35727363; PMCID: PMC10163916. [Article] NHE3 in the thick ascending limb is required for sustained but not acute furosemide-induced urinary acidification. Am J Physiol Renal Physiol.
Xue J, Thomas L, Dominguez Rieg JA, Fenton RA, Rieg T. Am J Physiol Renal Physiol. 2022 Aug 1;323(2):F141-F155. doi: 10.1152/ajprenal.00013.2022. Epub 2022 May 30. PMID: 35635321; PMCID: PMC9306792. [Article] Urinary extracellular vesicles: does cargo reflect tissue?
van Heugten MH, Hoorn EJ, Fenton RA. Curr Opin Nephrol Hypertens. 2022 Sep 1;31(5):464-470. doi: 10.1097/MNH.0000000000000822. Epub 2022 Jul 18. PMID: 35894281. [Article] COP9 signalosome deletion promotes renal injury and distal convoluted tubule remodeling.
Cornelius RJ, Nelson JW, Su XT, Yang CL, Ellison DH. Am J Physiol Renal Physiol. 2022 Jul 1;323(1):F4-F19. doi: 10.1152/ajprenal.00436.2021. Epub 2022 May 9. PMID: 35532068; PMCID: PMC9236871. [Article] KCC3a, a Strong Candidate Pathway for K+ Loss in Alkalemia.
Ferdaus MZ, Terker AS, Koumangoye R, Delpire E. Front Cell Dev Biol. 2022 Jul 7;10:931326. doi: 10.3389/fcell.2022.931326. PMID: 35874803; PMCID: PMC9301082. [Article] Mineralocorticoid Receptor Antagonists Cause Natriuresis in the Absence of Aldosterone’ in press in Hypertension (AHA)
- PMID: 35506380
- DOI: 10.1161/HYPERTENSIONAHA.122.19159
Kristensen M, Fenton RA, Poulsen SB. Front Physiol. 2022 Apr 26;13:800055. doi: 10.3389/fphys.2022.800055. PMID: 35557966; PMCID: PMC9086401. [Article] Aldosterone-producing adenoma associated with non-suppressed renin: a case series.
Jansen PM, Stowasser M. J Hum Hypertens 2022;36:376-80. [Article] Acute Intravenous NaCl and Volume Expansion Reduces Sodium-Chloride Cotransporter Abundance and Phosphorylation in Urinary Extracellular Vesicles.
Wu A, Wolley MJ, Wu Q, Cowley D, Palmfeldt J, Welling PA, Fenton RA, Stowasser M. Kidney360. 2022 Mar 1;3(5):910-921. doi: 10.34067/KID.0000362022. PMID: 36128481; PMCID: PMC9438418. [Article] Combined Kelch-like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice
Maeoka Y, Ferdaus MZ, Cornelius RJ, Sharma A, Su XT, Miller LN, Robertson JA, Gurley SB, Yang CL, Ellison DH, McCormick JA. J Am Soc Nephrol. 2022 Mar;33(3):584-600. doi: 10.1681/ASN.2021081099. Epub 2022 Jan 21.PMID: 35064051 [Article] Does the early aldosterone-induced SGK1 play a role in early Kaliuresis?
Al-Qusairi L, Basquin D, Stifanelli M, Welling PA, Staub O. Physiol Rep. 2022 Feb;10(4):e15188. doi: 10.14814/phy2.15188. PMID: 35224872; PMCID: PMC8883148. [Article] Pendrin-null mice develop severe hypokalemia following dietary Na+ and K+ restriction: role of ENaC.
Pham TD, Elengickal AJ, Verlander JW, Al-Qusairi L, Chen C, Abood DC, King SA, Loffing J, Welling PA, Wall SM. Am J Physiol Renal Physiol. 2022 May 1;322(5):F486-F497. doi: 10.1152/ajprenal.00378.2021. Epub 2022 Feb 28. PMID: 35224991; PMCID: PMC8977139. [Article] Low Salt Delivery Triggers Autocrine Release of Prostaglandin E2 From the Aldosterone-Sensitive Distal Nephron in Familial Hyperkalemic Hypertension Mice.
Zapf AM, Grimm PR, Al-Qusairi L, Delpire E, Welling PA. Front Physiol. 2022 Jan 6;12:787323. doi: 10.3389/fphys.2021.787323. PMID: 35069250; PMCID: PMC8770744. [Article]
2021
2020
2019
2018
2017
2016
2015
2014
2013
2011