Distal Convoluted Tubule Sexual Dimorphism Revealed by Advanced 3D-Imaging

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Ebrahim Tahaei, Richard Coleman, Turgay Saritas, David H. Ellison, and Paul A Welling. AJP Renal. 2020 Sep 14;doi.org/10.1152/ajprenal.00441.2020 Online ahead of print.

The single-cell transcriptomic landscape of early human diabetic nephropathy

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Wilson PC, Wu H, Kirita Y, Uchimura K, Ledru N, Rennke HG, Welling PA, Waikar SS, Humphreys BD. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19619-19625. doi: 10.1073/pnas.1908706116. Epub 2019 Sep 10. PMID: 31506348

Optical Clearing in the Kidney Reveals Potassium-Mediated Tubule Remodeling.

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Saritas T, Puelles VG, Su XT, McCormick JA, Welling PA, Ellison DH. Cell Rep. 2018 Dec 4;25(10):2668-2675.e3. doi: 10.1016/j.celrep.2018.11.021. PMID: 30517856 

Mechanism of Hyperkalemia-Induced Metabolic Acidosis

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Harris AN, Grimm PR, Lee HW, Delpire E, Fang L, Verlander JW, Welling PA, Weiner ID. J Am Soc Nephrol. 2018 May;29(5):1411-1425. doi: 10.1681/ASN.2017111163. Epub 2018 Feb 26. PMID: 29483157

Constitutively Active SPAK Causes Hyperkalemia by Activating NCC and Remodeling Distal Tubules

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Grimm PR, Coleman R, Delpire E, Welling PA. J Am Soc Nephrol. 2017 Sep;28(9):2597-2606. doi: 10.1681/ASN.2016090948. Epub 2017 Apr 25. PMID: 28442491

A Common Signal Patch Drives AP-1 Protein-dependent Golgi Export of Inwardly Rectifying Potassium Channel

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Li X, Ortega B, Kim B, Welling PA. J Biol Chem. 2016 Jul 15;291(29):14963-72. doi: 10.1074/jbc.M116.729822. Epub 2016 May 23. PMID: 27226616

Roles and Regulation of Renal K Channels

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Welling PA.Annu Rev Physiol. 2016;78:415-35. doi: 10.1146/annurev-physiol-021115-105423. Epub 2015 Dec 11. PMID: 26654186 Review.

Integrated compensatory network is activated in the absence of NCC phosphorylation

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Grimm PR, Lazo-Fernandez Y, Delpire E, Wall SM, Dorsey SG, Weinman EJ, Coleman R, Wade JB, Welling PA. J Clin Invest. 2015 May;125(5):2136-50. doi: 10.1172/JCI78558. Epub 2015 Apr 20. PMID: 25893600

SPAK-mediated NCC regulation in response to low-K+ diet

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Wade JB, Liu J, Coleman R, Grimm PR, Delpire E, Welling PA. Am J Physiol Renal Physiol. 2015 Apr 15;308(8):F923-31. doi: 10.1152/ajprenal.00388.2014. Epub 2015 Jan 28. PMID: 25651563

Short forms of Ste20-related proline/alanine-rich kinase (SPAK) in the kidney are created by aspartyl aminopeptidase (Dnpep)-mediated proteolytic cleavage

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Markadieu N, Rios K, Spiller BW, McDonald WH, Welling PA, Delpire E. J Biol Chem. 2014 Oct 17;289(42):29273-84. doi: 10.1074/jbc.M114.604009. Epub 2014 Aug 27. PMID: 25164821